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Cellular Fucosylation Inhibitors Based on Fluorinated Fucose‐1‐phosphates

Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a potential therapeutic avenue for example in cancer, inflammation, and infection. In this study, we found that protected 2‐fluorofucose 1‐phosphate efficiently inhibits c...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Pijnenborg, Johan F. A., Visser, Eline A., Noga, Marek, Rossing, Emiel, Veizaj, Raisa, Lefeber, Dirk J., Büll, Christian, Boltje, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986151/
https://ncbi.nlm.nih.gov/pubmed/33336886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202005359
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