Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma

Metabolism reprograming is a hallmark of cancer and plays an important role in tumor progression. The aberrant metabolism in renal cell carcinoma (RCC) leads to accumulation of the oncometabolite l‐2‐hydroxyglurate (L‐2HG). L‐2HG has been reported to inhibit the activity of some α‐ketoglutarate‐depe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Cancer
Egile Nagusiak: Wang, Huan, Wang, Liya, Zheng, Qiming, Lu, Zeyi, Chen, Yuanlei, Shen, Danyang, Xue, Dingwei, Jiang, Minxiao, Ding, Lifeng, Zhang, Jie, Wu, Haiyang, Xia, Liqun, Qian, Jun, Li, Gonghui, Lu, Jieyang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Inc. 2021
Gaiak:
Tumor Immunology and Microenvironment
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
https://ncbi.nlm.nih.gov/pubmed/33320958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33435
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