Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma

Metabolism reprograming is a hallmark of cancer and plays an important role in tumor progression. The aberrant metabolism in renal cell carcinoma (RCC) leads to accumulation of the oncometabolite l‐2‐hydroxyglurate (L‐2HG). L‐2HG has been reported to inhibit the activity of some α‐ketoglutarate‐depe...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Wang, Huan, Wang, Liya, Zheng, Qiming, Lu, Zeyi, Chen, Yuanlei, Shen, Danyang, Xue, Dingwei, Jiang, Minxiao, Ding, Lifeng, Zhang, Jie, Wu, Haiyang, Xia, Liqun, Qian, Jun, Li, Gonghui, Lu, Jieyang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
Assuntos:
Tumor Immunology and Microenvironment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
https://ncbi.nlm.nih.gov/pubmed/33320958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33435
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