Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma

Metabolism reprograming is a hallmark of cancer and plays an important role in tumor progression. The aberrant metabolism in renal cell carcinoma (RCC) leads to accumulation of the oncometabolite l‐2‐hydroxyglurate (L‐2HG). L‐2HG has been reported to inhibit the activity of some α‐ketoglutarate‐depe...

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Dades bibliogràfiques
Publicat a:Int J Cancer
Autors principals: Wang, Huan, Wang, Liya, Zheng, Qiming, Lu, Zeyi, Chen, Yuanlei, Shen, Danyang, Xue, Dingwei, Jiang, Minxiao, Ding, Lifeng, Zhang, Jie, Wu, Haiyang, Xia, Liqun, Qian, Jun, Li, Gonghui, Lu, Jieyang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2021
Matèries:
Tumor Immunology and Microenvironment
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
https://ncbi.nlm.nih.gov/pubmed/33320958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33435
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