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Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts
Conflicts between the replication and transcription machineries have profound effects on chromosome duplication, genome organization, and evolution across species. Head-on conflicts (lagging-strand genes) are significantly more detrimental than codirectional conflicts (leading-strand genes). The fun...
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| Publicado no: | Cell Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7986047/ https://ncbi.nlm.nih.gov/pubmed/33657379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108797 |
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