Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network

Sarcomas are a heterogeneous group of malignancies with mesenchymal lineage differentiation. The discovery of neurotrophic tyrosine receptor kinase (NTRK) gene fusions as tissue-agnostic oncogenic drivers has led to new personalized therapies for a subset of patients with sarcoma in the form of trop...

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Published in:Ann Oncol
Main Authors: Demetri, G. D., Antonescu, C. R., Bjerkehagen, B., Bovée, J. V. M. G., Boye, K., Chacón, M., Dei Tos, A. P., Desai, J., Fletcher, J. A., Gelderblom, H., George, S., Gronchi, A., Haas, R. L., Hindi, N., Hohenberger, P., Joensuu, H., Jones, R. L., Judson, I., Kang, Y.-K., Kawai, A., Lazar, A. J., Cesne, A. Le, Maestro, R., Maki, R. G., Martín, J., Patel, S., Penault-Llorca, F., Raut, C. Premanand, Rutkowski, P., Safwat, A., Sbaraglia, M., Schaefer, I.-M., Shen, L., Serrano, C., Schöffski, P., Stacchiotti, S., Hall, K. Sundby, Tap, W. D., Thomas, D. M., Trent, J., Valverde, C., van der Graaf, W. T. A., von Mehren, M., Wagner, A., Wardelmann, E., Naito, Y., Zalcberg, J., Blay, J.-Y.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985805/
https://ncbi.nlm.nih.gov/pubmed/32891793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annonc.2020.08.2232
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