Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions

HDL and its primary receptor, scavenger receptor class B type I (SR-BI), work together to promote the clearance of excess plasma cholesterol, thereby protecting against atherosclerosis. Human variants of SR-BI have been identified in patients with high HDL-cholesterol levels, and at least one varian...

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Foilsithe in:J Lipid Res
Main Authors: May, Sarah C., Dron, Jacqueline S., Hegele, Robert A., Sahoo, Daisy
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2021
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985710/
https://ncbi.nlm.nih.gov/pubmed/33577783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100045
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