Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function

BACKGROUND: Platelets release platelet-derived extracellular vesicles (PDEVs) upon activation – in a process that is regulated by generation of reactive oxygen species (ROS). Platelet NADPH oxidase-1 (Nox-1) contributes to ROS generation and thrombus formation downstream of the collagen receptor GPV...

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發表在:Free Radic Biol Med
Main Authors: Gaspar, Renato Simões, Ferreira, Plinio M., Mitchell, Joanne L., Pula, Giordano, Gibbins, Jonathan M.
格式: Artigo
語言:Inglês
出版: Elsevier Science 2021
主題:
Short Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985666/
https://ncbi.nlm.nih.gov/pubmed/33548451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.01.051
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