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Progression of prostate carcinoma is promoted by adipose stromal cell-secreted CXCL12 signaling in prostate epithelium

Aggressiveness of carcinomas is linked with tumor recruitment of adipose stromal cells (ASC), which is increased in obesity. ASC promote cancer through molecular pathways not fully understood. Here, we demonstrate that epithelial–mesenchymal transition (EMT) in prostate tumors is promoted by obesity...

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Su, Fei, Daquinag, Alexes C., Ahn, Songyeon, Saha, Achinto, Dai, Yulin, Zhao, Zhongming, DiGiovanni, John, Kolonin, Mikhail G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985375/
https://ncbi.nlm.nih.gov/pubmed/33753872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00160-9
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