Structural and functional brain-wide alterations in A350V Iqsec2 mutant mice displaying autistic-like behavior

IQSEC2 is an X-linked gene that is associated with autism spectrum disorder (ASD), intellectual disability, and epilepsy. IQSEC2 is a postsynaptic density protein, localized on excitatory synapses as part of the NMDA receptor complex and is suggested to play a role in AMPA receptor trafficking and m...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Lichtman, Daniela, Bergmann, Eyal, Kavushansky, Alexandra, Cohen, Nadav, Levy, Nina S., Levy, Andrew P., Kahn, Itamar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985214/
https://ncbi.nlm.nih.gov/pubmed/33753721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01289-8
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