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Potential Impact of DPYD Variation on Fluoropyrimidine Drug Response in sub-Saharan African Populations
Cancer is a critical health burden in Africa, and mortality rates are rising rapidly. Treatments are expensive and often cause adverse drug reactions (ADRs). Fluoropyrimidine treatments can lead to severe toxicity events which have been linked to variants within the dihydropyrimidine dehydrogenase (...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7985174/ https://ncbi.nlm.nih.gov/pubmed/33767731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.626954 |
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