Marine Peptide-N6NH2 and Its Derivative-GUON6NH2 Have Potent Antimicrobial Activity Against Intracellular Edwardsiella tarda in vitro and in vivo

Edwardsiella tarda is a facultative intracellular pathogen in humans and animals. There is no effective way except vaccine candidates to eradicate intracellular E. tarda. In this study, four derivatives of marine peptide-N6NH2 were designed by an introduction of unnatural residues or substitution of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Han, Huihui, Teng, Da, Mao, Ruoyu, Hao, Ya, Yang, Na, Wang, Zhenlong, Li, Ting, Wang, Xiumin, Wang, Jianhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985170/
https://ncbi.nlm.nih.gov/pubmed/33767681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.637427
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