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Binding Affinity and Function of the Extremely Disordered Protein Complex Containing Human Linker Histone H1.0 and Its Chaperone ProTα

It was recently reported that human linker histone H1.0 and its chaperone prothymosin-α (ProTα) form an extremely disordered 1:1 complex with an ultrahigh affinity (equilibrium dissociation constant K(D) of ∼2 × 10(−12) M) measured using a single-molecule Förster resonance energy transfer method. It...

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Vydáno v:Biochemistry
Hlavní autoři: Feng, Hanqiao, Zhou, Bing-Rui, Bai, Yawen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984725/
https://ncbi.nlm.nih.gov/pubmed/30430826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01075
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