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Binding Affinity and Function of the Extremely Disordered Protein Complex Containing Human Linker Histone H1.0 and Its Chaperone ProTα

It was recently reported that human linker histone H1.0 and its chaperone prothymosin-α (ProTα) form an extremely disordered 1:1 complex with an ultrahigh affinity (equilibrium dissociation constant K(D) of ∼2 × 10(−12) M) measured using a single-molecule Förster resonance energy transfer method. It...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Feng, Hanqiao, Zhou, Bing-Rui, Bai, Yawen
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984725/
https://ncbi.nlm.nih.gov/pubmed/30430826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01075
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