Pathogenic GRM7 Mutations Associated with Neurodevelopmental Disorders Impair Axon Outgrowth and Presynaptic Terminal Development

Metabotropic glutamate receptor 7 (mGlu7) is an inhibitory heterotrimeric G-protein-coupled receptor that modulates neurotransmitter release and synaptic plasticity at presynaptic terminals in the mammalian central nervous system. Recent studies have shown that rare mutations in glutamate receptors...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Song, Jae-man, Kang, Minji, Park, Da-ha, Park, Sunha, Lee, Sanghyeon, Suh, Young Ho
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984599/
https://ncbi.nlm.nih.gov/pubmed/33500274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2108-20.2021
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