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Modulation of cortical slow oscillatory rhythm by GABA(B) receptors: an in vitro experimental and computational study

KEY POINTS: We confirm that GABA(B) receptors (GABA(B)‐Rs) are involved in the termination of Up‐states; their blockade consistently elongates Up‐states. GABA(B)‐Rs also modulate Down‐states and the oscillatory cycle, thus having an impact on slow oscillation rhythm and its regularity. The most freq...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Perez‐Zabalza, Maria, Reig, Ramon, Manrique, Jesus, Jercog, Daniel, Winograd, Milena, Parga, Nestor, Sanchez‐Vives, Maria V.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984206/
https://ncbi.nlm.nih.gov/pubmed/32406934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP279476
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