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Deletion of the Trichoderma virens NRPS, Tex7, induces accumulation of the anti-cancer compound heptelidic acid

The anticancer antibiotic heptelidic acid is a sesquiterpene lactone produced by the beneficial plant fungus Trichoderma virens. This species has been separated into two strains, referred to as P and Q, based on its biosynthesis of secondary metabolites; notably, only P-strains were reported to prod...

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Библиографические подробности
Опубликовано в: :Biochem Biophys Res Commun
Главные авторы: Taylor, James T., Mukherjee, Prasun K., Puckhaber, Lorraine S., Dixit, Karuna, Igumenova, Tatyana I., Suh, Charles, Horwitz, Benjamin A., Kenerley, Charles M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983848/
https://ncbi.nlm.nih.gov/pubmed/32736691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.06.040
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