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Adaptive sample size determination for the development of clinical prediction models

BACKGROUND: We suggest an adaptive sample size calculation method for developing clinical prediction models, in which model performance is monitored sequentially as new data comes in. METHODS: We illustrate the approach using data for the diagnosis of ovarian cancer (n = 5914, 33% event fraction) an...

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Detalhes bibliográficos
Publicado no:Diagn Progn Res
Main Authors: Christodoulou, Evangelia, van Smeden, Maarten, Edlinger, Michael, Timmerman, Dirk, Wanitschek, Maria, Steyerberg, Ewout W., Van Calster, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983402/
https://ncbi.nlm.nih.gov/pubmed/33745449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41512-021-00096-5
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