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Chitosan Hydrogels for Synergistic Delivery of Chemotherapeutics to Triple Negative Breast Cancer Cells and Spheroids

PURPOSE: This study aimed to develop a hydrogel system for treating aggressive triple negative breast cancer (TNBC) via kinetically-controlled delivery of the synergistic drug pair doxorubicin (DOX) and gemcitabine (GEM). A 2D assay was adopted to evaluate therapeutic efficacy by determining combina...

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Publicado en:Pharm Res
Autores principales: Schneible, John D., Young, Ashlyn T., Daniele, M. A., Menegatti, S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983306/
https://ncbi.nlm.nih.gov/pubmed/32661774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02864-2
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