A 193-Amino Acid Fragment of the SARS Coronavirus S Protein Efficiently Binds Angiotensin-converting Enzyme 2

The coronavirus spike (S) protein mediates infection of receptor-expressing host cells and is a critical target for antiviral neutralizing antibodies. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for the coronavirus (severe acute respiratory syndrome (SARS)-CoV) that causes SARS....

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Wong, Swee Kee, Li, Wenhui, Moore, Michael J., Choe, Hyeryun, Farzan, Michael
Format: Artigo
Language:Inglês
Published: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2004
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982343/
https://ncbi.nlm.nih.gov/pubmed/14670965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C300520200
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