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Cytochrome P450 2C19 enzyme, Cytochrome P450 2C9 enzyme, and Cytochrome P450 2D6 enzyme allelic variants and its possible effect on drug metabolism: A retrospective study

The objective of the present study was to assess the allelic variations of Cytochrome P450 (CYP) enzymes Cytochrome P450 2C19 (CYP2C19), Cytochrome P450 2C9 (CYP2C9), and Cytochrome P450 2D6 (CYP2D6) as they play a major role in drug metabolism. The interindividual genetic variabilities of these enz...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Naujokaitis, Domas, Asmoniene, Virginija, Kadusevicius, Edmundas
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982200/
https://ncbi.nlm.nih.gov/pubmed/33725937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000024545
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