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The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli

BACKGROUND: Significant efforts have been made in building large-scale kinetic models of cellular metabolism in the past two decades. However, most kinetic models published to date, remain focused around central carbon pathways or are built around ad hoc reduced models without clear justification on...

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Publicat a:BMC Bioinformatics
Autors principals: Hameri, Tuure, Fengos, Georgios, Hatzimanikatis, Vassily
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981984/
https://ncbi.nlm.nih.gov/pubmed/33743594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04066-y
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