Chitosan hydrogel-loaded MSC-derived extracellular vesicles promote skin rejuvenation by ameliorating the senescence of dermal fibroblasts

BACKGROUND: The senescence of dermal fibroblasts (DFLs) leads to an imbalance in the synthesis and degradation of extracellular matrix (ECM) proteins, presenting so-called senescence-associated secretory phenotype (SASP), which ultimately leads to skin aging. Recently, mesenchymal stem cell (MSC)-de...

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Dades bibliogràfiques
Publicat a:Stem Cell Res Ther
Autors principals: Zhao, Xiangnan, Liu, Yue, Jia, Pingping, Cheng, Hui, Wang, Chen, Chen, Shang, Huang, Haoyan, Han, Zhibo, Han, Zhong-Chao, Marycz, Krzysztof, Chen, Xiaoniao, Li, Zongjin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981922/
https://ncbi.nlm.nih.gov/pubmed/33743829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02262-4
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