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Effects of Interleukin-1β Inhibition on Incident Anemia: Exploratory Analyses From a Randomized Trial

BACKGROUND: Inflammatory cytokines, such as interleukin (IL)-1β, alter iron homeostasis and erythropoiesis, resulting in anemia, but whether inhibition of IL-1β can reverse these effects is unclear. OBJECTIVE: To determine whether IL-1β inhibition with canakinumab reduces incident anemia and improve...

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Detalhes bibliográficos
Publicado no:Ann Intern Med
Main Authors: Vallurupalli, Mounica, MacFadyen, Jean G., Glynn, Robert J., Thuren, Tom, Libby, Peter, Berliner, Nancy, Ridker, Paul M
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980674/
https://ncbi.nlm.nih.gov/pubmed/32203978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M19-2945
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