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Long-read assembly of a Great Dane genome highlights the contribution of GC-rich sequence and mobile elements to canine genomes

Technological advances have allowed improvements in genome reference sequence assemblies. Here, we combined long- and short-read sequence resources to assemble the genome of a female Great Dane dog. This assembly has improved continuity compared to the existing Boxer-derived (CanFam3.1) reference ge...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Halo, Julia V., Pendleton, Amanda L., Shen, Feichen, Doucet, Aurélien J., Derrien, Thomas, Hitte, Christophe, Kirby, Laura E., Myers, Bridget, Sliwerska, Elzbieta, Emery, Sarah, Moran, John V., Boyko, Adam R., Kidd, Jeffrey M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980453/
https://ncbi.nlm.nih.gov/pubmed/33836575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016274118
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