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Antigenic cartography reveals complexities of genetic determinants that lead to antigenic differences among pandemic GII.4 noroviruses

Noroviruses are the predominant cause of acute gastroenteritis, with a single genotype (GII.4) responsible for the majority of infections. This prevalence is characterized by the periodic emergence of new variants that present substitutions at antigenic sites of the major structural protein (VP1), f...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kendra, Joseph A., Tohma, Kentaro, Ford-Siltz, Lauren A., Lepore, Cara J., Parra, Gabriel I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980451/
https://ncbi.nlm.nih.gov/pubmed/33836574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015874118
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