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Antigenic cartography reveals complexities of genetic determinants that lead to antigenic differences among pandemic GII.4 noroviruses

Noroviruses are the predominant cause of acute gastroenteritis, with a single genotype (GII.4) responsible for the majority of infections. This prevalence is characterized by the periodic emergence of new variants that present substitutions at antigenic sites of the major structural protein (VP1), f...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Kendra, Joseph A., Tohma, Kentaro, Ford-Siltz, Lauren A., Lepore, Cara J., Parra, Gabriel I.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980451/
https://ncbi.nlm.nih.gov/pubmed/33836574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015874118
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