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Revealing lineage-related signals in single-cell gene expression using random matrix theory

Gene expression profiles of a cellular population, generated by single-cell RNA sequencing, contains rich information about biological state, including cell type, cell cycle phase, gene regulatory patterns, and location within the tissue of origin. A major challenge is to disentangle information abo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nitzan, Mor, Brenner, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980374/
https://ncbi.nlm.nih.gov/pubmed/33836557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913931118
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