Stress undermines reward-guided cognitive performance through synaptic depression in the lateral habenula

Weighing alternatives during reward pursuit is a vital cognitive computation that, when disrupted by stress, yields aspects of neuropsychiatric disorders. To examine the neural mechanisms underlying these phenomena, we employed a behavioral task in which mice were confronted by a reward and its omis...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Nuno-Perez, Alvaro, Trusel, Massimo, Lalive, Arnaud L., Congiu, Mauro, Gastaldo, Denise, Tchenio, Anna, Lecca, Salvatore, Soiza-Reilly, Mariano, Bagni, Claudia, Mameli, Manuel
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2021
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980092/
https://ncbi.nlm.nih.gov/pubmed/33535028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.01.008
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