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Development of a functional salivary gland tissue chip with potential for high-content drug screening

Radiation therapy for head and neck cancers causes salivary gland dysfunction leading to permanent xerostomia. Limited progress in the discovery of new therapeutic strategies is attributed to the lack of in vitro models that mimic salivary gland function and allow high-throughput drug screening. We...

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Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Song, Yuanhui, Uchida, Hitoshi, Sharipol, Azmeer, Piraino, Lindsay, Mereness, Jared A., Ingalls, Matthew H., Rebhahn, Jonathan, Newlands, Shawn D., DeLouise, Lisa A., Ovitt, Catherine E., Benoit, Danielle S. W.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979686/
https://ncbi.nlm.nih.gov/pubmed/33742114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01876-x
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