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New Avenues for Phosphodiesterase Inhibitors in Asthma

INTRODUCTION: Phosphodiesterases (PDEs) are isoenzymes ubiquitously expressed in the lungs where they catalyse cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (GMP), which are fundamental second messengers in asthma, thereby regulating the intracellular concentrations of the...

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Détails bibliographiques
Publié dans:J Exp Pharmacol
Auteurs principaux: Matera, Maria Gabriella, Ora, Josuel, Cavalli, Francesco, Rogliani, Paola, Cazzola, Mario
Format: Artigo
Langue:Inglês
Publié: Dove 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979323/
https://ncbi.nlm.nih.gov/pubmed/33758554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JEP.S242961
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