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Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies

BACKGROUND: A recent randomised trial showed that recombinant thrombomodulin did not benefit patients who had sepsis with coagulopathy and organ dysfunction. Several recent studies suggested presence of clinical phenotypes in patients with sepsis and heterogenous treatment effects across different s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Kudo, Daisuke, Goto, Tadahiro, Uchimido, Ryo, Hayakawa, Mineji, Yamakawa, Kazuma, Abe, Toshikazu, Shiraishi, Atsushi, Kushimoto, Shigeki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978458/
https://ncbi.nlm.nih.gov/pubmed/33741010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-021-03541-5
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