Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza

Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly understood. We have used novel mouse models of co-infect...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Barman, Tarani Kanta, Racine, Rachael, Bonin, Jesse L., Califano, Danielle, Salmon, Sharon L., Metzger, Dennis W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978370/
https://ncbi.nlm.nih.gov/pubmed/33690728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009405
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