Vertebral-specific activation of the CX3CL1/ICAM-1 signaling network mediates non-small-cell lung cancer spinal metastasis by engaging tumor cell-vertebral bone marrow endothelial cell interactions

Rationale: The spine is one of the most common metastatic sites of non-small cell lung cancer (NSCLC), and NSCLC spinal metastasis results in serious consequences. Metastatic extravasation of disseminated cancer cells including increased invasiveness, adhesion and transendothelial migration is cruci...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wang, Ketao, Jiang, Libo, Hu, Annan, Sun, Chi, Zhou, Lei, Huang, Yiwei, Chen, Qing, Dong, Jian, Zhou, Xiaogang, Zhang, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978319/
https://ncbi.nlm.nih.gov/pubmed/33754027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.54235
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