Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus

OBJECTIVE: Hydroxychloroquine (HCQ) is a mainstay of therapy in the treatment of SLE. The effect of HCQ on platelets and vascular health is uncertain. We investigated the relationship between HCQ use and dose with platelet activity, platelet transcriptomics and vascular health in patients with SLE....

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Publicado en:Lupus Sci Med
Autores principales: Cornwell, MacIntosh Grant, Luttrell-Williams, Elliot S, Golpanian, Michael, El Bannoudi, Hanane, Myndzar, Khrystyna, Izmirly, Peter, Belmont, H Michael, Katz, Stuart, Smilowitz, Nathaniel R, Engel, Alexis, Clancy, Robert, Ruggles, Kelly, Buyon, Jill P, Berger, Jeffrey S
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2021
Materias:
Biomarker Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978255/
https://ncbi.nlm.nih.gov/pubmed/33737451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2021-000475
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