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Glycocalyx components affect platelet function, whole blood coagulation, and fibrinolysis: an in vitro study suggesting a link to trauma-induced coagulopathy

BACKGROUND: The mechanisms of trauma induced coagulopathy (TIC) are considered multifactorial. Amongst others, however, shedding of the endothelial glycocalyx resulting in increased concentrations of glycocalyx fragments in plasma might also play a role. Thus, we hypothesized that shedded glycocalyx...

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Pubblicato in:BMC Anesthesiol
Autori principali: Britten, Martin W., Lümers, Laura, Tominaga, Kenji, Peters, Jürgen, Dirkmann, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977584/
https://ncbi.nlm.nih.gov/pubmed/33740916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-021-01300-1
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