Pectin supplement significantly enhanced the anti-PD-1 efficacy in tumor-bearing mice humanized with gut microbiota from patients with colorectal cancer

Background: Anti-PD-1-based immunotherapy has emerged as a promising therapy for several cancers. However, it only benefits a small subset of colorectal cancer (CRC) patients. Mounting data supports the pivotal role of gut microbiota in shaping immune system. Pectin, a widely consumed soluble fiber,...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhang, Shi-Long, Mao, Yu-Qin, Zhang, Zheng-Yan, Li, Zhan-Ming, Kong, Chao-Yue, Chen, Hui-Ling, Cai, Pei-Ran, Han, Bing, Ye, Tao, Wang, Li-Shun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977465/
https://ncbi.nlm.nih.gov/pubmed/33754054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.54476
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