A Commonly Used Biocide 2-N-octyl-4-isothiazolin-3-oneInduces Blood–Brain Barrier Dysfunction via Cellular Thiol Modification and Mitochondrial Damage

Isothiazolinone (IT) biocides are potent antibacterial substances commonly used as preservatives or disinfectants, and 2-n-Octyl-4-isothiazolin-3-one (OIT; octhilinone) is a common IT biocide that is present in leather products, glue, paints, and cleaning products. Although humans are exposed to OIT...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Donghyun, Kim, Eun-Hye, Choi, Sungbin, Lim, Kyung-Min, Tie, Lu, Majid, Arshad, Bae, Ok-Nam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7975974/
https://ncbi.nlm.nih.gov/pubmed/33806369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052563
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