Advanced pharmacological therapies for neurofibromatosis type 1-related tumors

Neurofibromatosis Type 1 (NF1) is an autosomal dominant tumor-predisposition disorder that is caused by a heterozygous loss of function variant in the NF1 gene, which encodes a protein called neurofibromin. The absence of neurofibromin causes increased activity in the Rat sarcoma protein (RAS) signa...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Biomed
Hauptverfasser: Foiadelli, Thomas, Naso, Matteo, Licari, Amelia, Orsini, Alessandro, Magistrali, Mariasole, Trabatti, Chiara, Luzzi, Sabino, Mosconi, Mario, Savasta, Salvatore, Marseglia, Gian Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mattioli 1885 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7975824/
https://ncbi.nlm.nih.gov/pubmed/32608378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23750/abm.v91i7-S.9961
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