New Cutoffs for the Biochemical Diagnosis of Adrenal Insufficiency after ACTH Stimulation using Specific Cortisol Assays

CONTEXT: The normal cortisol response 30 or 60 minutes after cosyntropin (ACTH([1–24])) is considered to be ≥18 μg/dL (500 nmol/L). This threshold is based on older serum cortisol assays. Specific monoclonal antibody immunoassays or LC-MS/MS may have lower thresholds for a normal response. OBJECTIVE...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Endocr Soc
Main Authors: Javorsky, Bradley R, Raff, Hershel, Carroll, Ty B, Algeciras-Schimnich, Alicia, Singh, Ravinder Jit, Colón-Franco, Jessica M, Findling, James W
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Clinical Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7975762/
https://ncbi.nlm.nih.gov/pubmed/33768189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab022
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