Anterior gradient 2 increases long-chain fatty acid uptake via stabilizing FABP1 and facilitates lipid accumulation

Anterior gradient 2 (AGR2), a protein disulfide isomerase (PDI), is a well-established oncogene. Here, we found that Agr2(-/-) mice had a decreased fat mass and hepatic and serum lipid levels compared with their wild-type littermates after fasting, and exhibited reduced high-fat diet (HFD)-induced f...

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Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Wang, Yunqiu, Jia, Mengqi, Liang, Chuanjie, Sheng, Nan, Wang, Xiaodan, Wang, Fang, Luo, Yanhai, Jiang, Jin, Cai, Liangyu, Niu, Huanmin, Zhu, Deyu, Nesa, Effat Un, Young, Charles YF, Yuan, Huiqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7975708/
https://ncbi.nlm.nih.gov/pubmed/33767592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.57099
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