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Brucine inhibits proliferation of glioblastoma cells by targeting the G-quadruplexes in the c-Myb promoter
The proto-oncogene c-Myb plays an important role in cell proliferation, and its upregulation affects the development of glioblastomas. G-quadruplexes are secondary DNA or RNA structures that usually form in the promoter region of oncogenes, including c-Myb, and regulate the expression of these genes...
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| Publicado no: | J Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7974541/ https://ncbi.nlm.nih.gov/pubmed/33753997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.53689 |
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