Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF-κB signaling

Cigarette smoke (CS) exposure is a risk factor for dyslipidemia and atherosclerosis. Reduced expression of low-density lipoprotein receptor (LDLR) in hepatocytes may be one of the underlying mechanisms for these disorders. The aim of the present study was to investigate the molecular mechanism under...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Ma, Baitao, Wang, Xuebin, Zhang, Rui, Niu, Shuai, Rong, Zhihua, Ni, Leng, Di, Xiao, Han, Qin, Liu, Changwei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974406/
https://ncbi.nlm.nih.gov/pubmed/33760160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11970
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