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Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate

In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify non-antibiotic substances with broad-spectrum activity able to destroy the EPS matrix and enhance the effect of antibiotics...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Liu, JingJing, Madec, Jean-Yves, Bousquet-Mélou, Alain, Haenni, Marisa, Ferran, Aude A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973569/
https://ncbi.nlm.nih.gov/pubmed/33737602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85722-4
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