The TOMM40 ‘523’ polymorphism in disease risk and age of symptom onset in two independent cohorts of Parkinson’s disease

Abnormal mitochondrial function is a key process in the pathogenesis of Parkinson’s disease (PD). The central pore-forming protein TOM40 of the mitochondria is encoded by the translocase of outer mitochondrial membrane 40 homologue gene (TOMM40). The highly variant ‘523’ poly-T repeat is associated...

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Publicat a:Sci Rep
Autors principals: Bakeberg, Megan C., Hoes, Madison E., Gorecki, Anastazja M., Theunissen, Frances, Pfaff, Abigail L., Kenna, Jade E., Plunkett, Kai, Kõks, Sulev, Akkari, P. Anthony, Mastaglia, Frank L., Anderton, Ryan S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973542/
https://ncbi.nlm.nih.gov/pubmed/33737565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85510-0
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