Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction

The administration of extracellular vesicles (EV) from mesenchymal stromal cells (MSC) is a promising cell-free nanotherapy for tissue repair after myocardial infarction (MI). However, the optimal EV delivery strategy remains undetermined. Here, we designed a novel MSC-EV delivery, using 3D scaffold...

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Vydáno v:Bioact Mater
Hlavní autoři: Monguió-Tortajada, Marta, Prat-Vidal, Cristina, Moron-Font, Miriam, Clos-Sansalvador, Marta, Calle, Alexandra, Gastelurrutia, Paloma, Cserkoova, Adriana, Morancho, Anna, Ramírez, Miguel Ángel, Rosell, Anna, Bayes-Genis, Antoni, Gálvez-Montón, Carolina, Borràs, Francesc E., Roura, Santiago
Médium: Artigo
Jazyk:Inglês
Vydáno: KeAi Publishing 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973387/
https://ncbi.nlm.nih.gov/pubmed/33778207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2021.02.026
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