Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture

The study of transcriptional regulation is still difficult yet fundamental in molecular biology research. Recent research has shown that the double helix structure of nucleotides plays an important role in improving the accuracy and interpretability of transcription factor binding sites (TFBSs). Alt...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Wang, Siguo, Zhang, Qinhu, Shen, Zhen, He, Ying, Chen, Zhen-Heng, Li, Jianqiang, Huang, De-Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972936/
https://ncbi.nlm.nih.gov/pubmed/33767912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.02.014
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