The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with Mycobacterium avium subsp. paratuberculosis

Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic enteritis of ruminants. Previous studies have shown that programmed death-ligand 1 (PD-L1) is associated with the disease progression, and PD-L1 blockade activates MAP-specific Th1 responses in vitro. Here, we...

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Dettagli Bibliografici
Pubblicato in:J Vet Med Sci
Autori principali: SAJIKI, Yamato, KONNAI, Satoru, NAGATA, Reiko, KAWAJI, Satoko, NAKAMURA, Hayato, FUJISAWA, Sotaro, OKAGAWA, Tomohiro, MAEKAWA, Naoya, KATO, Yukinari, SUZUKI, Yasuhiko, MURATA, Shiro, MORI, Yasuyuki, OHASHI, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Society of Veterinary Science 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972883/
https://ncbi.nlm.nih.gov/pubmed/33281144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.20-0590
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