CircFAM73A promotes the cancer stem cell-like properties of gastric cancer through the miR-490-3p/HMGA2 positive feedback loop and HNRNPK-mediated β-catenin stabilization

BACKGROUND: Circular RNAs (circRNAs) have emerged as a new subclass of regulatory RNAs that play critical roles in various cancers. Cancer stem cells (CSCs), a small subset of cancer cells, are believed to possess the capacities to initiate tumorigenesis and promote progression. Although accumulatin...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Xia, Yiwen, Lv, Jialun, Jiang, Tianlu, Li, Bowen, Li, Ying, He, Zhongyuan, Xuan, Zhe, Sun, Guangli, Wang, Sen, Li, Zheng, Wang, Weizhi, Wang, Linjun, Xu, Zekuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972245/
https://ncbi.nlm.nih.gov/pubmed/33731207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01896-9
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