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Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices

Cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) show great potential for engineering myocardium to study cardiac disease and create regenerative therapies. However, iPSC-CMs typically possess a late embryonic stage phenotype, with cells failing to exhibit markers of mature adul...

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Detalles Bibliográficos
Publicado en:Biomater Sci
Main Authors: DePalma, Samuel J., Davidson, Christopher D., Stis, Austin E., Helms, Adam S., Baker, Brendon M.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971708/
https://ncbi.nlm.nih.gov/pubmed/33325920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0bm01247e
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