Genomic amplification of long noncoding RNA HOTAIRM1 drives anaplastic thyroid cancer progression via repressing miR-144 biogenesis

Genomic aberrations are frequently found in anaplastic thyroid cancer (ATC). However, the functional genes in aberrantly genomic regions are largely unclear. In this study, we identified a long noncoding RNA (lncRNA) HOTAIRM1, whose encoding gene was amplified and expression was upregulated in ATC c...

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Zhang, Ling, Zhang, Jin, Li, Shujing, Zhang, Yanyan, Liu, Yun, Dong, Jian, Zhao, Wenjun, Yu, Bo, Wang, Huifang, Liu, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971326/
https://ncbi.nlm.nih.gov/pubmed/32951513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1819670
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