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Metabolic engineering of probiotic Escherichia coli for cytolytic therapy of tumors
Bacterial cancer therapy was developed using probiotic Escherichia coli Nissle 1917 (EcN) for medical intervention of colorectal cancer. EcN was armed with HlyE, a small cytotoxic protein, under the control of the araBAD promoter (P(BAD)). The intrinsic limitation of P(BAD) for the gene expression i...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7971005/ https://ncbi.nlm.nih.gov/pubmed/33712706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85372-6 |
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