Preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates

COVID-19 outbreak caused by SARS-CoV-2 created an unprecedented health crisis since there is no vaccine for this novel virus. Therefore, SARS-CoV-2 vaccines have become crucial for reducing morbidity and mortality. In this study, in vitro and in vivo safety and efficacy analyzes of lyophilized vacci...

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Vydáno v:Sci Rep
Hlavní autoři: Sir Karakus, Gozde, Tastan, Cihan, Dilek Kancagi, Derya, Yurtsever, Bulut, Tumentemur, Gamze, Demir, Sevda, Turan, Raife Dilek, Abanuz, Selen, Cakirsoy, Didem, Seyis, Utku, Ozer, Samed, Elibol, Omer, Elek, Muhammer, Ertop, Gurcan, Arbak, Serap, Acikel Elmas, Merve, Hemsinlioglu, Cansu, Kocagoz, Ayse Sesin, Hatirnaz Ng, Ozden, Akyoney, Sezer, Sahin, Ilayda, Ozbek, Ugur, Telci, Dilek, Sahin, Fikrettin, Yalcin, Koray, Ratip, Siret, Ovali, Ercument
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970959/
https://ncbi.nlm.nih.gov/pubmed/33707532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83930-6
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