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Omics data integration identifies ELOVL7 and MMD gene regions as novel loci for adalimumab response in patients with Crohn’s disease

Response to anti-TNF therapy is of pivotal importance in patients with Crohn’s disease (CD). Here we integrated our and previously reported PBMC derived transcriptomic and genomic data for identification of biomarkers for discrimination between responders and non-responders to anti-TNF therapy. CD p...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Gorenjak, Mario, Zupin, Mateja, Jezernik, Gregor, Skok, Pavel, Potočnik, Uroš
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970911/
https://ncbi.nlm.nih.gov/pubmed/33750834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84909-z
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